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The Continental Disc IntegrX-HPX™ rupture disc addresses the need within the biopharmaceutical industry to improve process performance, reliability, and safety. The pioneering and innovative IntegrX-HPX combines the unrivaled performance of the legendary HPX with ASME BPE compliant crevice-free inlet design, removing the need for integral seals. Traditional sanitary rupture disc designs limit access to the full spectrum of benefits delivered by HPX technology. The IntegrX-HPX is a semi-circular, scored, reverse-acting rupture disc, perfectly suited for cyclic process conditions from full vacuum to 90-95% of the stamped rating. Its welded design mitigates the impact of downstream piping loads on the rupture disc burst pressure and overall performance. Continental Disc incorporated an external tag, aiding installation and providing clearly visible identification in the field and easy access to marked data. IntegrX-HPX rupture disc offers a unique opportunity to boost efficiency, safety, and keep cost down by utilizing legendary HPX service life. The bold new design reduces maintenance, minimizes the chance of installation damage, and allows you to control the source and type of seal material without affecting rupture disc performance.